Search results for "Quality development"
showing 3 items of 3 documents
Manufacturing, characterization and control of cell-based medicinal products: challenging paradigms toward commercial use
2015
During the past decade, a large number of cell-based medicinal products have been tested in clinical trials for the treatment of various diseases and tissue defects. However, licensed products and those approaching marketing authorization are still few. One major area of challenge is the manufacturing and quality development of these complex products, for which significant manipulation of cells might be required. While the paradigms of quality, safety and efficacy must apply also to these innovative products, their demonstration may be demanding. Demonstration of comparability between production processes and batches may be difficult for cell-based medicinal products. Thus, the development …
Quality management in the public sector accounting department - (un)avoidable quality costs and unlikely financial impacts
2017
This paper investigates the nature of quality costs and the likelihood of their having financial impacts in the public sector. An illustrative quality development case project in an accounting department of a Finnish city administration is presented. The empirical data includes answers to a qualitative project question sheet, workshop material and participative observation. Quality problems are classified according to their quality cost category and the extent to which they are avoidable. Some of the quality costs proved unavoidable and some are likely to lack financial impact, exhibiting sticky cost behaviour. The study indicates that certain prevention and appraisal costs in the public se…
Desorganización del apego y el trastorno traumático del desarrollo (ttd)
2014
Abstract:DISRUPTION OF ATTACHMENT AND TRAUMATIC DISORDER OF DEVELOPMENTQuality development of family members depends on the quality of relationships they have established. From this developmental perspective the early parent-child interactions are a central aspect of Bowlby’s attachment theory. Mary Ainsworth allows us to establish a classification of attachment behaviors and Main and Solomon bring us under the name of disorganized attachment more complex and disturbing profiles of relations between parents and children. These relationships should be asymmetric and have a unique sense. In this paper we show the contributions related to disorganized attachment, its relationship to personalit…